Basic Information
ID: ALA4723292
Type: ADME
Description: Hepatic extraction ratio in rat liver microsomes preincubated for 3 mins followed by NADPH addition and measured after 60 mins
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4715854
Hepatic extraction ratio in rat liver microsomes preincubated for 3 mins followed by NADPH addition and measured after 60 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4723292
ERH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.49 | 5.35 | 5.35 |
| 463.58 | 3.65 | 3.65 |
| 446.56 | 4.18 | 4.18 |
| 444.32 | 4.76 | 4.76 |
| 308.30 | 1.54 | 1.54 |
| 351.37 | 2.54 | 2.54 |
| 457.49 | 3.27 | 3.27 |
| 431.40 | 3.11 | 3.11 |
| 493.57 | 1.53 | 1.53 |
| 381.39 | 2.17 | 2.17 |
| 321.34 | 2.54 | 2.54 |
| 464.53 | 3.10 | 3.10 |
| 423.43 | 1.81 | 1.81 |
| 392.42 | 2.12 | 2.12 |
| 350.30 | 3.29 | 3.29 |
| 460.50 | 2.60 | 2.60 |
| 365.35 | 1.77 | 1.77 |
| 337.34 | 1.64 | 1.64 |
| 420.47 | 2.50 | 2.50 |
| 495.54 | 1.81 | 1.81 |
| 519.61 | 2.78 | 2.78 |
| 477.55 | 3.64 | 3.64 |
| 479.54 | 2.74 | 2.74 |
| 321.34 | 2.45 | 2.45 |
| 394.44 | 2.09 | 2.09 |
| 467.53 | 1.36 | 1.36 |
| 347.38 | 3.02 | 3.02 |
| 479.50 | 1.57 | 1.57 |
| 449.39 | 3.19 | 3.19 |
| 493.52 | 1.56 | 1.56 |
| 341.76 | 2.80 | 2.80 |
| 364.41 | 2.21 | 2.21 |
| 307.31 | 2.15 | 2.15 |
| 410.43 | 1.70 | 1.70 |
| 365.39 | 2.93 | 2.93 |
| 507.55 | 1.44 | 1.44 |
| 425.45 | 2.32 | 2.32 |
| 308.30 | 1.54 | 1.54 |
| 352.27 | 2.74 | 2.74 |
| 411.42 | 1.66 | 1.66 |
| 509.39 | 6.80 | 6.80 |
| 423.43 | 1.81 | 1.81 |
| 345.28 | 3.71 | 3.71 |
| 544.70 | 3.74 | 3.74 |
| 398.42 | 1.90 | 1.90 |
| 420.47 | 3.59 | 3.59 |
| 354.37 | 1.89 | 1.89 |
| 366.43 | 2.27 | 2.27 |
| 353.09 | 4.45 | 4.45 |
| 430.42 | 3.14 | 3.14 |
| 520.59 | 2.75 | 2.75 |
| 521.58 | 1.83 | 1.83 |
| 479.54 | 2.57 | 2.57 |
| 322.33 | 1.73 | 1.73 |
| 353.34 | 1.31 | 1.31 |
| 361.28 | 3.42 | 3.42 |
| 507.60 | 2.35 | 2.35 |
| 521.58 | 1.83 | 1.83 |
| 521.58 | 1.83 | 1.83 |
| 478.55 | 3.69 | 3.69 |
| 520.59 | 1.87 | 1.87 |
| 486.55 | 2.32 | 2.32 |
| 465.51 | 2.18 | 2.18 |
| 462.51 | 3.06 | 3.06 |
| 337.34 | 2.15 | 2.15 |
| 546.55 | 3.91 | 3.91 |
| 559.65 | 1.49 | 1.49 |
| 507.55 | 1.44 | 1.44 |
| 486.52 | 4.05 | 4.05 |
| 523.59 | 2.08 | 2.08 |
| 460.29 | 2.93 | 2.93 |
| 466.50 | 2.15 | 2.15 |
| 493.57 | 2.82 | 2.82 |
| 484.51 | 3.80 | 3.80 |
| 521.58 | 1.83 | 1.83 |
| 520.59 | 1.87 | 1.87 |
| 535.61 | 2.22 | 2.22 |
| 480.53 | 1.16 | 1.16 |
| 509.57 | 1.69 | 1.69 |
| 449.52 | 2.94 | 2.94 |