Basic Information
ID: ALA4723935
Type: Binding
Description: Selectivity ratio of inhibition of human sGC expressed in HUVEC cells assessed as reduction in GMP level at 20 uM in presence of NPS to inhibition of human sGC expressed in HUVEC cells assessed as reduction in GMP level at 20 uM in presence of NPS/BAY-412272
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HUVEC
Target: Unchecked(ALA612545)
Document: ALA4715872
Selectivity ratio of inhibition of human sGC expressed in HUVEC cells assessed as reduction in GMP level at 20 uM in presence of NPS to inhibition of human sGC expressed in HUVEC cells assessed as reduction in GMP level at 20 uM in presence of NPS/BAY-412272: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4723935
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 546.53 | 3.32 | 3.32 |