Basic Information
ID: ALA4724042
Type: Binding
Description: Inhibition of PI3Kalpha in human MDA-MB-453 cells assessed as reduction in phosphorylation of AKT at 473 at 10 uM measured after 1 hr by alpha screen assay
Organism: Homo sapiens
Cell type: MDA-MB-453
Activity Charts
Bioactivity
Activity Types for Assay ALA4724042
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.43 | 3.10 | 3.10 |
| 400.42 | 3.52 | 3.52 |
| 400.42 | 3.52 | 3.52 |
| 436.40 | 3.80 | 3.80 |
| 400.42 | 3.95 | 3.95 |
| 447.45 | 3.55 | 3.55 |
| 451.41 | 3.38 | 3.38 |
| 509.52 | 4.91 | 4.91 |
| 414.44 | 3.83 | 3.83 |
| 428.47 | 4.14 | 4.14 |
| 396.45 | 3.69 | 3.69 |
| 418.41 | 3.66 | 3.66 |
| 521.56 | 4.78 | 4.78 |