Basic Information
ID: ALA4724043
Type: Binding
Description: Inhibition of PI3Kbeta in human 786-O cells assessed as reduction in phosphorylation of AKT at 473 measured after 1 hr by alpha screen assay
Organism: Homo sapiens
Cell type: 786-0
Activity Charts
Bioactivity
Activity Types for Assay ALA4724043
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.43 | 4.26 | 4.26 |
| 508.53 | 5.64 | 5.64 |
| 415.43 | 3.10 | 3.10 |
| 400.42 | 3.52 | 3.52 |
| 375.41 | 3.65 | 3.65 |
| 414.44 | 3.83 | 3.83 |
| 400.42 | 3.52 | 3.52 |
| 458.47 | 4.54 | 4.54 |
| 491.53 | 4.77 | 4.77 |
| 436.40 | 3.80 | 3.80 |
| 400.42 | 3.95 | 3.95 |
| 447.45 | 3.55 | 3.55 |
| 534.56 | 3.87 | 3.87 |
| 396.45 | 3.69 | 3.69 |
| 455.50 | 3.98 | 3.98 |
| 451.41 | 3.38 | 3.38 |
| 429.46 | 3.41 | 3.41 |
| 451.41 | 3.38 | 3.38 |
| 382.43 | 3.81 | 3.81 |
| 509.52 | 4.91 | 4.91 |
| 433.42 | 3.24 | 3.24 |
| 396.45 | 4.11 | 4.11 |
| 473.49 | 4.12 | 4.12 |
| 396.45 | 4.11 | 4.11 |
| 414.44 | 3.83 | 3.83 |
| 433.42 | 3.24 | 3.24 |
| 428.47 | 4.14 | 4.14 |
| 414.44 | 3.83 | 3.83 |
| 396.45 | 3.69 | 3.69 |
| 429.46 | 3.41 | 3.41 |
| 418.41 | 3.66 | 3.66 |
| 415.43 | 3.10 | 3.10 |
| 521.56 | 4.78 | 4.78 |
| 432.43 | 3.97 | 3.97 |