Assay Report Card

Basic Information

ID: ALA4724197

Type: Functional

Description: Antitumor activity against human BT474 cells xenografted in athymic nude mouse assessed as suppression of tumor growth by measuring decrease in number of Ki67 positive cells at 50 mg/kg, po administered via oral gavage for 5 times per week for 55 days measured post-last dose by Ki67-staining based immunohistochemistry

Organism: Homo sapiens

Cell type: BT-474

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
558.016.296.29
536.055.765.76