Basic Information
ID: ALA4724637
Type: ADME
Description: Inhibition of CYP2D6 (unknown origin) assessed as formation of 4'-hydroxybufuralol at 10 uM using bufuralol as substrate relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4715902
Inhibition of CYP2D6 (unknown origin) assessed as formation of 4'-hydroxybufuralol at 10 uM using bufuralol as substrate relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4724637
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.96 | 4.39 | 4.39 |
| 463.92 | 4.20 | 4.20 |
| 431.91 | 3.75 | 3.75 |
| 417.88 | 3.36 | 3.36 |
| 444.95 | 3.67 | 3.67 |
| 435.87 | 3.50 | 3.50 |
| 458.98 | 4.06 | 4.06 |
| 445.93 | 4.14 | 4.14 |
| 435.87 | 3.50 | 3.50 |
| 449.90 | 3.81 | 3.81 |
| 401.88 | 4.12 | 4.12 |