Basic Information
ID: ALA4724661
Type: Binding
Description: Protac activity at CRBN/IRAK4 in human OCILY10 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation at 1 uM in presence of IRAK4 inhibitor, Methyl 4-(5-ethoxy-1-methyl-6-(6-(trifluoromethyl)picolinamido)-1H-benzo[d]imidazol-2-yl)-2,2-dimethylbutanoate by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OCILY10
Target: Protein cereblon/IRAK4(ALA4523710)
Document: ALA4715903
Protac activity at CRBN/IRAK4 in human OCILY10 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation at 1 uM in presence of IRAK4 inhibitor, Methyl 4-(5-ethoxy-1-methyl-6-(6-(trifluoromethyl)picolinamido)-1H-benzo[d]imidazol-2-yl)-2,2-dimethylbutanoate by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4724661
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 864.88 | 4.26 | 4.26 |