Assay Report Card

Basic Information

ID: ALA4724662

Type: Binding

Description: Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation at 1 uM in presence of CRBN recruiter, pomalidomide by Western blot analysis

Organism: Homo sapiens

Cell type: TMD8

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
864.884.264.26