Basic Information
ID: ALA4724665
Type: Binding
Description: Protac activity at CRBN/IRAK4 in human OCILY10 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation at 1 uM pretreated with proteasome inhibitor, MG132 for 2 hrs followed by compound addition by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OCILY10
Target: Protein cereblon/IRAK4(ALA4523710)
Document: ALA4715903
Protac activity at CRBN/IRAK4 in human OCILY10 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation at 1 uM pretreated with proteasome inhibitor, MG132 for 2 hrs followed by compound addition by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4724665
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 864.88 | 4.26 | 4.26 |