Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IR...

Basic Information

ID: ALA4724666

Type: Binding

Description: Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level at 1 uM by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: TMD8

Target:  Protein cereblon/IRAK4(ALA4523710)

Document:  ALA4715903

Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level at 1 uM by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
864.884.264.26