Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IR...

Basic Information

ID: ALA4724668

Type: Binding

Description: Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level incubated for 24 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: TMD8

Target:  Protein cereblon/IRAK4(ALA4523710)

Document:  ALA4715903

Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level incubated for 24 hrs by Western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
864.884.264.26