Basic Information
ID: ALA4725002
Type: Binding
Description: Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptake
Organism: Homo sapiens
Cell type: COS7
Activity Charts
Bioactivity
Activity Types for Assay ALA4725002
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.60 | 2.51 | 2.51 |
| 364.40 | -0.20 | -0.20 |
| 392.45 | 0.44 | 0.44 |
| 396.47 | 0.21 | 0.21 |
| 408.45 | 0.28 | 0.28 |
| 394.42 | -0.11 | -0.11 |
| 380.40 | -0.50 | -0.50 |
| 378.43 | 0.05 | 0.05 |
| 450.53 | 1.33 | 1.33 |
| 408.45 | 0.27 | 0.27 |
| 392.45 | 0.61 | 0.61 |
| 410.49 | 0.46 | 0.46 |
| 450.44 | 0.92 | 0.92 |
| 364.40 | -0.20 | -0.20 |
| 364.40 | -0.20 | -0.20 |
| 422.48 | 0.29 | 0.29 |
| 400.43 | 0.53 | 0.53 |
| 422.48 | 0.29 | 0.29 |
| 436.51 | 0.77 | 0.77 |
| 450.53 | 1.16 | 1.16 |
| 364.40 | -0.32 | -0.32 |
| 378.43 | 0.07 | 0.07 |
| 350.37 | -0.51 | -0.51 |
| 424.52 | 1.02 | 1.02 |