Basic Information
ID: ALA4725100
Type: Binding
Description: Inhibition of GST-tagged MDM2 (23 to 117 residues) (unknown origin) assessed as inhibition of MDM2/biotinylated wild type human p53 (16 to 27 residues) interaction by measuring reactivation of p53 incubated for 15 mins by AlphaScreen assay
Format: BAO_0000224
Organism: Homo sapiens
Target: Tumour suppressor p53/oncoprotein Mdm2(ALA1907611)
Document: ALA4715930
Inhibition of GST-tagged MDM2 (23 to 117 residues) (unknown origin) assessed as inhibition of MDM2/biotinylated wild type human p53 (16 to 27 residues) interaction by measuring reactivation of p53 incubated for 15 mins by AlphaScreen assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4725100
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.43 | 5.40 | 5.40 |
| 692.62 | 6.09 | 6.09 |
| 607.47 | 6.01 | 6.01 |
| 671.56 | 7.58 | 7.58 |
| 577.44 | 6.00 | 6.00 |
| 685.59 | 6.56 | 6.56 |
| 672.54 | 6.98 | 6.98 |
| 591.47 | 6.39 | 6.39 |
| 604.51 | 6.05 | 6.05 |
| 577.44 | 6.00 | 6.00 |
| 551.41 | 5.61 | 5.61 |
| 673.62 | 6.87 | 6.87 |