Basic Information
ID: ALA4725171
Type: Binding
Description: Displacement of Tracer 222 from N-terminal GST-tagged human recombinant HPK1 (1 to 346 residues ) expressed in baculovirus-infected Sf9 cells incubated for 1 hr by HTRF lanthascreen binding assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Mitogen-activated protein kinase kinase kinase kinase 1(ALA5749)
Document: ALA4715933
Displacement of Tracer 222 from N-terminal GST-tagged human recombinant HPK1 (1 to 346 residues ) expressed in baculovirus-infected Sf9 cells incubated for 1 hr by HTRF lanthascreen binding assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4725171
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.50 | 3.82 | 3.82 |
| 400.50 | 4.89 | 4.89 |
| 390.42 | 2.78 | 2.78 |
| 417.49 | 3.99 | 3.99 |
| 399.50 | 3.19 | 3.19 |
| 405.43 | 3.47 | 3.47 |
| 400.49 | 2.58 | 2.58 |
| 403.42 | 3.76 | 3.76 |
| 401.49 | 4.29 | 4.29 |
| 383.50 | 4.15 | 4.15 |
| 425.51 | 4.76 | 4.76 |
| 462.49 | 3.52 | 3.52 |
| 400.49 | 3.24 | 3.24 |
| 387.44 | 3.33 | 3.33 |
| 319.34 | 4.24 | 4.24 |
| 418.48 | 3.38 | 3.38 |
| 389.43 | 4.23 | 4.23 |
| 432.50 | 3.77 | 3.77 |
| 418.48 | 3.38 | 3.38 |
| 404.45 | 3.04 | 3.04 |
| 452.92 | 4.04 | 4.04 |
| 417.49 | 3.99 | 3.99 |
| 443.56 | 3.60 | 3.60 |
| 461.50 | 3.09 | 3.09 |
| 431.52 | 4.38 | 4.38 |
| 444.51 | 3.82 | 3.82 |
| 335.34 | 3.21 | 3.21 |
| 418.48 | 3.38 | 3.38 |
| 456.57 | 4.19 | 4.19 |
| 369.47 | 3.84 | 3.84 |
| 419.46 | 2.78 | 2.78 |
| 350.35 | 3.64 | 3.64 |
| 430.49 | 3.52 | 3.52 |
| 442.50 | 3.86 | 3.86 |
| 404.45 | 4.07 | 4.07 |
| 444.51 | 3.91 | 3.91 |
| 397.53 | 4.46 | 4.46 |
| 403.46 | 4.62 | 4.62 |
| 323.33 | 2.97 | 2.97 |