Basic Information
ID: ALA4725175
Type: Binding
Description: Inhibition of HPK1 in human PBMC assessed as unbound concentration required for inhibition of SLP76 phosphorylation by ELISA corrected to binding to 10% FBS
Format: BAO_0000357
Organism: Homo sapiens
Target: Mitogen-activated protein kinase kinase kinase kinase 1(ALA5749)
Document: ALA4715933
Inhibition of HPK1 in human PBMC assessed as unbound concentration required for inhibition of SLP76 phosphorylation by ELISA corrected to binding to 10% FBS: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4725175
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.51 | 4.76 | 4.76 |
| 418.48 | 3.38 | 3.38 |
| 432.50 | 3.77 | 3.77 |
| 430.49 | 3.52 | 3.52 |
| 442.50 | 3.86 | 3.86 |
| 444.51 | 3.91 | 3.91 |