Basic Information
ID: ALA4726289
Type: Binding
Description: Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in HMGCR-dCat-Eluc protein level after 4 hrs by luciferase reporter assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4726289
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.54 | 7.82 | 7.82 |
| 560.65 | 9.37 | 9.37 |
| 562.67 | 8.94 | 8.94 |
| 488.54 | 8.11 | 8.11 |
| 557.65 | 8.25 | 8.25 |
| 547.65 | 8.63 | 8.63 |
| 506.56 | 7.39 | 7.39 |
| 625.73 | 9.19 | 9.19 |
| 514.58 | 7.92 | 7.92 |
| 448.43 | 6.52 | 6.52 |
| 616.45 | 8.54 | 8.54 |
| 499.49 | 7.56 | 7.56 |
| 531.57 | 8.88 | 8.88 |
| 505.57 | 7.20 | 7.20 |
| 392.33 | 5.22 | 5.22 |
| 543.62 | 7.86 | 7.86 |
| 546.67 | 9.24 | 9.24 |