Basic Information
ID: ALA4726492
Type: Binding
Description: Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafil
Format: BAO_0000221
Organism: Homo sapiens
Cell type: Platelet
Target: Phosphodiesterase 5A(ALA1827)
Document: ALA4725271
Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafil: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4726492
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.59 | 1.61 | 1.61 |
| 383.21 | 3.24 | 3.24 |
| 332.37 | 2.30 | 2.30 |
| 360.42 | 3.95 | 3.95 |
| 362.35 | 2.39 | 2.39 |
| 425.29 | 4.33 | 4.33 |
| 425.29 | 4.33 | 4.33 |
| 333.35 | 2.43 | 2.43 |
| 346.39 | 3.56 | 3.56 |
| 376.37 | 2.47 | 2.47 |
| 439.31 | 4.72 | 4.72 |
| 412.25 | 3.19 | 3.19 |
| 411.26 | 3.07 | 3.07 |
| 304.31 | 2.48 | 2.48 |
| 346.39 | 3.56 | 3.56 |