Basic Information
ID: ALA4727044
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled ligand from His6-thr-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant (unknown origin) after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4727044
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.45 | 4.16 | 4.16 |
| 463.58 | 3.67 | 3.67 |
| 449.60 | 3.64 | 3.64 |
| 385.47 | 0.92 | 0.92 |
| 459.59 | 3.74 | 3.74 |
| 383.50 | 1.93 | 1.93 |
| 423.56 | 3.10 | 3.10 |
| 477.61 | 2.81 | 2.81 |
| 382.51 | 2.68 | 2.68 |
| 477.61 | 3.98 | 3.98 |
| 385.47 | 0.92 | 0.92 |
| 465.60 | 2.87 | 2.87 |
| 465.62 | 3.80 | 3.80 |
| 449.56 | 3.33 | 3.33 |
| 463.59 | 2.47 | 2.47 |
| 449.56 | 3.33 | 3.33 |
| 369.47 | 1.68 | 1.68 |
| 357.46 | 1.39 | 1.39 |
| 477.61 | 3.98 | 3.98 |
| 383.50 | 2.07 | 2.07 |
| 465.62 | 3.80 | 3.80 |
| 463.63 | 4.03 | 4.03 |
| 493.68 | 4.45 | 4.45 |
| 371.49 | 1.78 | 1.78 |
| 477.61 | 3.98 | 3.98 |
| 479.65 | 4.14 | 4.14 |
| 474.61 | 3.44 | 3.44 |
| 385.47 | 0.92 | 0.92 |
| 373.46 | 0.77 | 0.77 |
| 383.50 | 2.07 | 2.07 |
| 355.44 | 1.15 | 1.15 |
| 493.68 | 4.45 | 4.45 |
| 449.56 | 3.33 | 3.33 |
| 493.68 | 4.45 | 4.45 |
| 448.57 | 3.94 | 3.94 |