Basic Information
ID: ALA4727317
Type: Functional
Description: Antagonist activity at human V1a receptor expressed in human 1321N1 cells assessed as decrease in Arg8-vasopressin-stimulated calcium flux by fluorometric calcium assay
Organism: Homo sapiens
Cell type: 1321N1
Activity Charts
Bioactivity
Activity Types for Assay ALA4727317
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.97 | 4.52 | 4.52 |
| 409.92 | 4.37 | 4.37 |
| 437.97 | 3.83 | 3.83 |
| 385.90 | 3.61 | 3.61 |
| 357.85 | 2.91 | 2.91 |
| 412.92 | 3.76 | 3.76 |
| 392.29 | 3.56 | 3.56 |
| 428.92 | 2.69 | 2.69 |
| 480.05 | 5.00 | 5.00 |
| 383.92 | 4.73 | 4.73 |
| 439.97 | 4.92 | 4.92 |
| 466.03 | 4.61 | 4.61 |
| 466.03 | 5.33 | 5.33 |
| 370.88 | 3.82 | 3.82 |
| 474.99 | 5.01 | 5.01 |
| 370.88 | 3.46 | 3.46 |
| 467.01 | 4.89 | 4.89 |
| 369.90 | 4.34 | 4.34 |
| 370.88 | 3.43 | 3.43 |
| 384.91 | 3.80 | 3.80 |
| 439.99 | 4.08 | 4.08 |
| 336.44 | 3.17 | 3.17 |
| 369.90 | 4.88 | 4.88 |
| 440.98 | 4.35 | 4.35 |
| 448.98 | 3.13 | 3.13 |
| 412.92 | 3.72 | 3.72 |
| 383.88 | 4.21 | 4.21 |
| 371.87 | 3.30 | 3.30 |
| 370.88 | 3.82 | 3.82 |
| 438.96 | 4.11 | 4.11 |
| 466.03 | 5.33 | 5.33 |
| 703.88 | 5.59 | 5.59 |
| 384.91 | 3.85 | 3.85 |
| 371.87 | 3.22 | 3.22 |
| 406.32 | 3.59 | 3.59 |
| 370.88 | 3.51 | 3.51 |
| 355.87 | 3.95 | 3.95 |