Basic Information
ID: ALA4727488
Type: Binding
Description: Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha production
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4727488
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.47 | 3.76 | 3.76 |
| 396.47 | 3.18 | 3.18 |
| 364.45 | 3.79 | 3.79 |
| 397.45 | 3.22 | 3.22 |
| 396.47 | 3.18 | 3.18 |
| 384.46 | 2.91 | 2.91 |
| 368.42 | 2.13 | 2.13 |
| 391.52 | 4.08 | 4.08 |
| 356.41 | 2.13 | 2.13 |
| 370.43 | 2.65 | 2.65 |
| 370.43 | 2.65 | 2.65 |
| 393.50 | 2.75 | 2.75 |
| 395.48 | 3.86 | 3.86 |
| 382.44 | 2.66 | 2.66 |