Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM

Basic Information

ID: ALA4727728

Type: Binding

Description: Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM

Format: BAO_0000219

Organism: Mus musculus

Cell type: J774.A1

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA3779755)

Document:  ALA4725325

Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
232.323.553.55
248.322.362.36
232.323.243.24
248.322.762.76
232.323.243.24