Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM

Basic Information

ID: ALA4727729

Type: Binding

Description: Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Primary neuron

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA4725325

Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 1 to 10 uM: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
232.323.553.55
248.322.362.36
232.323.243.24
248.322.762.76
232.323.243.24