Basic Information
ID: ALA4727731
Type: Binding
Description: Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release
Organism: Homo sapiens
Cell type: Primary neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA4727731
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.38 | 0.97 | 0.97 |
| 248.32 | 2.36 | 2.36 |
| 547.63 | 2.29 | 2.29 |
| 561.66 | 2.68 | 2.68 |
| 248.32 | 2.76 | 2.76 |
| 547.63 | 1.88 | 1.88 |
| 561.66 | 2.27 | 2.27 |