Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 10 uM in presence of PTL/MCL

Basic Information

ID: ALA4727740

Type: Binding

Description: Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 10 uM in presence of PTL/MCL

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Primary neuron

Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document: ALA4725325

Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 10 uM in presence of PTL/MCL: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4727740

Inhibition

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
234.20	2.78	2.78
553.60	4.49	4.49
553.60	4.90	4.90

Parent Molecular Weight

ALogP

Polar Surface Area

234.20

2.78

553.60

4.49

553.60

4.90

Inhibition of NLRP3 inflammasome in human primary glial cells assessed as reduction in LPS-induced IL-1beta release at 10 uM in presence of PTL/MCL

Basic Information

Activity Charts

Compound Summary