Basic Information
ID: ALA4728139
Type: ADME
Description: Intrinsic clearance in Han Wistar rat hepatocytes assessed per million cells at 1 uM by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Han Wistar
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA4728139
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 296.33 | 1.93 | 1.93 |
| 322.29 | 3.38 | 3.38 |
| 329.43 | 2.30 | 2.30 |
| 274.27 | 3.26 | 3.26 |
| 288.38 | 3.23 | 3.23 |
| 286.34 | 2.04 | 2.04 |
| 328.32 | 3.14 | 3.14 |
| 340.31 | 2.58 | 2.58 |
| 339.29 | 1.87 | 1.87 |
| 280.34 | 2.70 | 2.70 |
| 324.27 | 2.17 | 2.17 |
| 274.35 | 2.98 | 2.98 |
| 302.41 | 3.76 | 3.76 |
| 251.60 | 1.98 | 1.98 |
| 406.42 | 2.82 | 2.82 |
| 272.34 | 2.37 | 2.37 |
| 246.30 | 2.20 | 2.20 |
| 268.35 | 4.03 | 4.03 |
| 323.40 | 2.24 | 2.24 |
| 330.36 | 4.47 | 4.47 |
| 327.70 | 3.65 | 3.65 |
| 302.36 | 1.99 | 1.99 |
| 314.42 | 3.90 | 3.90 |
| 309.26 | 2.47 | 2.47 |
| 314.30 | 3.13 | 3.13 |
| 294.36 | 3.09 | 3.09 |
| 300.39 | 3.15 | 3.15 |
| 329.43 | 2.67 | 2.67 |
| 376.26 | 4.09 | 4.09 |
| 308.27 | 3.07 | 3.07 |
| 324.27 | 2.17 | 2.17 |
| 293.25 | 2.99 | 2.99 |
| 323.28 | 3.00 | 3.00 |
| 309.38 | 1.85 | 1.85 |
| 315.30 | 1.08 | 1.08 |
| 300.33 | 0.67 | 0.67 |
| 300.39 | 3.51 | 3.51 |
| 326.29 | 2.29 | 2.29 |
| 324.33 | 4.41 | 4.41 |
| 260.33 | 2.59 | 2.59 |
| 368.39 | 3.94 | 3.94 |
| 336.37 | 3.39 | 3.39 |
| 286.36 | 2.76 | 2.76 |
| 272.34 | 2.73 | 2.73 |
| 333.28 | 2.94 | 2.94 |
| 376.34 | 3.59 | 3.59 |
| 338.29 | 3.08 | 3.08 |
| 288.38 | 3.37 | 3.37 |
| 300.27 | 3.09 | 3.09 |
| 244.23 | 1.82 | 1.82 |
| 329.33 | 1.47 | 1.47 |
| 338.29 | 3.08 | 3.08 |
| 311.24 | 3.13 | 3.13 |
| 342.35 | 3.91 | 3.91 |
| 322.29 | 3.38 | 3.38 |
| 310.24 | 1.86 | 1.86 |
| 315.41 | 1.91 | 1.91 |
| 310.24 | 1.86 | 1.86 |
| 322.29 | 3.10 | 3.10 |
| 326.29 | 1.81 | 1.81 |
| 326.26 | 3.21 | 3.21 |
| 342.71 | 3.72 | 3.72 |
| 312.26 | 1.80 | 1.80 |
| 310.24 | 1.86 | 1.86 |
| 274.35 | 2.98 | 2.98 |
| 377.25 | 3.48 | 3.48 |