Assay Report Card

Basic Information

ID: ALA4728770

Type: Binding

Description: Negative allosteric modulation of human GluN1a/GluN2A receptor expressed in CHO cells assessed as inhibition of glutamate and glycine-induced calcium flux preincubated for 5 mins followed by glutamate and glycine addition and measured after 5 mins by calcium 5 dye based FLIPR assay

Organism: Homo sapiens

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
376.342.692.69
396.392.712.71