Basic Information
ID: ALA4728771
Type: Binding
Description: Negative allosteric modulation of human GluN1a/GluN2C receptor expressed in CHO cells assessed as inhibition of glutamate and glycine-induced calcium flux preincubated for 5 mins followed by glutamate and glycine addition and measured after 5 mins by calcium 5 dye based FLIPR assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4728771
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.34 | 2.69 | 2.69 |
| 396.39 | 2.71 | 2.71 |