Basic Information
ID: ALA4728927
Type: Binding
Description: Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by Eu-labeled anti-His antibody addition and measured after 90 mins by FRET based LanthaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4728927
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.03 | 4.52 | 4.52 |
| 404.92 | 4.22 | 4.22 |
| 339.46 | 5.01 | 5.01 |
| 338.48 | 5.05 | 5.05 |
| 467.56 | 3.86 | 3.86 |
| 339.46 | 5.01 | 5.01 |
| 434.95 | 4.23 | 4.23 |
| 481.58 | 3.87 | 3.87 |
| 439.37 | 4.87 | 4.87 |
| 400.50 | 3.58 | 3.58 |
| 442.54 | 3.95 | 3.95 |
| 404.92 | 4.22 | 4.22 |
| 467.56 | 3.86 | 3.86 |
| 404.92 | 4.22 | 4.22 |
| 401.49 | 2.97 | 2.97 |
| 482.57 | 3.26 | 3.26 |
| 422.91 | 4.36 | 4.36 |
| 373.91 | 5.67 | 5.67 |
| 354.48 | 4.60 | 4.60 |
| 468.54 | 4.12 | 4.12 |
| 435.94 | 3.62 | 3.62 |
| 339.46 | 5.01 | 5.01 |
| 478.58 | 4.53 | 4.53 |
| 481.58 | 3.87 | 3.87 |
| 401.49 | 2.97 | 2.97 |
| 388.92 | 5.25 | 5.25 |
| 458.54 | 3.14 | 3.14 |
| 338.48 | 5.05 | 5.05 |
| 422.91 | 4.36 | 4.36 |
| 339.46 | 5.01 | 5.01 |
| 439.37 | 4.87 | 4.87 |
| 404.92 | 4.22 | 4.22 |
| 488.92 | 5.12 | 5.12 |