Basic Information
ID: ALA4729127
Type: Binding
Description: Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4729127
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.60 | 4.47 | 4.47 |
| 507.61 | 5.50 | 5.50 |
| 587.65 | 4.78 | 4.78 |
| 521.63 | 5.89 | 5.89 |
| 531.58 | 4.62 | 4.62 |
| 573.54 | 4.47 | 4.47 |
| 613.73 | 6.70 | 6.70 |
| 507.61 | 5.50 | 5.50 |
| 537.63 | 5.13 | 5.13 |
| 587.65 | 4.78 | 4.78 |
| 587.65 | 4.78 | 4.78 |
| 587.65 | 4.78 | 4.78 |
| 587.65 | 4.78 | 4.78 |
| 559.51 | 4.08 | 4.08 |
| 617.59 | 4.48 | 4.48 |
| 587.65 | 4.78 | 4.78 |
| 603.56 | 4.09 | 4.09 |
| 573.54 | 4.47 | 4.47 |
| 507.61 | 5.50 | 5.50 |
| 537.63 | 5.13 | 5.13 |
| 565.69 | 5.91 | 5.91 |
| 493.58 | 5.11 | 5.11 |
| 537.63 | 5.13 | 5.13 |
| 551.66 | 5.52 | 5.52 |
| 561.65 | 5.13 | 5.13 |
| 587.65 | 4.78 | 4.78 |
| 535.66 | 6.28 | 6.28 |
| 587.65 | 4.78 | 4.78 |
| 507.61 | 5.50 | 5.50 |
| 507.61 | 5.50 | 5.50 |