Assay Report Card

Basic Information

ID: ALA4729135

Type: Binding

Description: Agonist activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
523.604.474.47
587.654.784.78
617.594.484.48