Basic Information
ID: ALA4729138
Type: Binding
Description: Agonist activity at zebrafish GPR34 type b expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis
Format: BAO_0000219
Organism: Danio rerio
Cell type: HEK293
Target: G protein-coupled receptor 34b(ALA4739857)
Document: ALA4725358
Agonist activity at zebrafish GPR34 type b expressed in HEK293 cells co-transfected with AP-TGFalpha/Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr by p-NPP substrate based microplate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4729138
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.60 | 4.47 | 4.47 |
| 587.65 | 4.78 | 4.78 |
| 617.59 | 4.48 | 4.48 |