Basic Information
ID: ALA4729271
Type: Binding
Description: Negative allosteric modulator activity at human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 assessed as Kcat for cGMP at 25 nM incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting method (Rvb = 2.53 +/- 0.24 /s)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4729271
Kcat
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.42 | 3.33 | 3.33 |