Basic Information
ID: ALA4729292
Type: Binding
Description: Inhibition of N-terminal biotin-labeled BIM BH3 peptide (141 to 166 residues) binding to His-tagged Mcl-1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for >=30 mins by fluorescence polarization
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4729292
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 850.05 | 6.05 | 6.05 |
| 245.29 | 3.78 | 3.78 |
| 273.34 | 4.27 | 4.27 |
| 335.41 | 5.30 | 5.30 |
| 317.39 | 4.29 | 4.29 |
| 349.44 | 5.61 | 5.61 |
| 353.40 | 5.44 | 5.44 |
| 365.44 | 5.33 | 5.33 |
| 299.38 | 4.66 | 4.66 |
| 385.47 | 6.45 | 6.45 |
| 241.60 | ||
| 379.46 | 5.47 | 5.47 |
| 349.44 | 5.49 | 5.49 |