Basic Information
ID: ALA4729457
Type: Binding
Description: Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation at 10 uM by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4729457
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 801.95 | 2.67 | 2.67 |
| 917.08 | 2.20 | 2.20 |
| 796.97 | 3.69 | 3.69 |
| 890.05 | 2.71 | 2.71 |
| 873.02 | 2.18 | 2.18 |
| 846.00 | 2.69 | 2.69 |
| 828.97 | 2.16 | 2.16 |
| 768.92 | 2.91 | 2.91 |