Assay Report Card

Basic Information

ID: ALA4729476

Type: Binding

Description: Protac activity at CRBN/IRAK3 in LPS-induced human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs by HPLC-MS based global proteomic analysis relative to control

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
878.093.353.35