Protac activity at CRBN/IRAK4 in LPS-induced human THP1 cells assessed as induction of IRAK4 degradation at 0.1 uM measured after 6 hrs by HPLC-MS bas...

Basic Information

ID: ALA4729479

Type: Binding

Description: Protac activity at CRBN/IRAK4 in LPS-induced human THP1 cells assessed as induction of IRAK4 degradation at 0.1 uM measured after 6 hrs by HPLC-MS based global proteomic analysis

Format: BAO_0000221

Organism: Homo sapiens

Cell type: THP-1

Target:  Protein cereblon/IRAK4(ALA4523710)

Document:  ALA4725370

Protac activity at CRBN/IRAK4 in LPS-induced human THP1 cells assessed as induction of IRAK4 degradation at 0.1 uM measured after 6 hrs by HPLC-MS based global proteomic analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
878.093.353.35