Assay Report Card

Basic Information

ID: ALA4729485

Type: Binding

Description: Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM preincubated for 16 hrs followed by compound washout and measured after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
878.093.353.35