Assay Report Card

Basic Information

ID: ALA4729486

Type: Binding

Description: Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
878.093.353.35