ID: ALA4729487
Type: Binding
Description: Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of NEDD8-activating enzyme inhibitor MLN4924 by Western blot analysis
Organism: Homo sapiens
Cell type: THP-1
Bioactivity
Activity Types for Assay ALA4729487
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
878.09 | 3.35 | 3.35 |