Basic Information
ID: ALA4729488
Type: Binding
Description: Protac activity at CRBN/IRAK3 in human THP1 cells assessed as induction of IRAK3 degradation at 0.1 uM measured after 6 hrs in presence of IRAK3 ligand cis-1-(4-(4-((5-Isopropylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-cyclohexyl)piperazin-1-yl)ethanone by Western blot analysis
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4729488
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 878.09 | 3.35 | 3.35 |