Assay Report Card

Basic Information

ID: ALA4729491

Type: Binding

Description: Protac activity at CRBN/IRAK3 in human PBMC derived primary macrophages assessed as induction of IRAK3 degradation at 0.3 uM measured after 8 to 32 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: Primary macrophage

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
878.093.353.35
892.123.693.69