Basic Information
ID: ALA4729492
Type: Binding
Description: Protac activity at CRBN/IRAK3 in human PBMC derived primary macrophages assessed as induction of IRAK3 degradation at 0.3 uM preincubated for 8 hrs followed by LPS-stimulation and measured after 8 to 32 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: Primary macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4729492
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 878.09 | 3.35 | 3.35 |
| 892.12 | 3.69 | 3.69 |