Basic Information
ID: ALA4729680
Type: Binding
Description: Noncompetitive inhibition of recombinant human SARM1 TIR domain (561 to 724 residues) expressed in Escherichia coli C43 (DE3) cells lysates assessed as EADPR formation using ENAD as substrate preincubated for 20 mins followed by ENAD addition and measured at 15 sec interval for 1 hr
Organism: Homo sapiens
Subcellular Fraction: Lysates
Activity Charts
Bioactivity
Activity Types for Assay ALA4729680
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.82 | 3.10 | 3.10 |
| 198.14 | 0.19 | 0.19 |
| 480.90 | -0.35 | -0.35 |