Basic Information
ID: ALA4729692
Type: Functional
Description: Selectivity index, ratio of IC50 for wild-type human U251 cells to IC50 for human U251 cells overexpressing EPHA2 assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Format: BAO_0000221
Organism: Homo sapiens
Cell type: U-251
Target: Unchecked(ALA612545)
Document: ALA4725378
Selectivity index, ratio of IC50 for wild-type human U251 cells to IC50 for human U251 cells overexpressing EPHA2 assessed as reduction in cell viability incubated for 48 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4729692
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.46 | 1.77 | 1.77 |
| 438.44 | 2.10 | 2.10 |
| 472.89 | 2.75 | 2.75 |
| 772.95 | 4.67 | 4.67 |
| 442.91 | 2.43 | 2.43 |
| 1019.09 | ||
| 898.98 | 4.05 | 4.05 |
| 660.74 | 1.55 | 1.55 |
| 676.74 | 0.79 | 0.79 |
| 913.01 | 4.44 | 4.44 |
| 408.46 | 1.77 | 1.77 |
| 858.96 | 5.74 | 5.74 |
| 452.47 | 2.41 | 2.41 |
| 899.02 | 6.66 | 6.66 |
| 408.46 | 1.77 | 1.77 |
| 914.98 | 3.29 | 3.29 |
| 914.98 | 3.29 | 3.29 |
| 674.76 | 1.94 | 1.94 |
| 438.44 | 2.10 | 2.10 |
| 943.03 | 3.91 | 3.91 |
| 472.89 | 2.75 | 2.75 |
| 913.01 | 4.44 | 4.44 |
| 442.91 | 2.43 | 2.43 |
| 422.49 | 2.08 | 2.08 |
| 983.87 | 4.60 | 4.60 |
| 930.98 | 4.49 | 4.49 |
| 438.44 | 2.10 | 2.10 |
| 692.73 | 1.99 | 1.99 |