Basic Information
ID: ALA4729978
Type: Binding
Description: Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins by malachite green reagent based assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4729978
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.23 | -1.64 | -1.64 |
| 563.83 | 1.07 | 1.07 |
| 580.83 | 2.35 | 2.35 |
| 477.84 | 0.99 | 0.99 |
| 534.29 | 1.56 | 1.56 |
| 537.89 | -0.02 | -0.02 |
| 531.81 | 1.54 | 1.54 |
| 463.82 | 0.61 | 0.61 |
| 561.32 | 1.00 | 1.00 |
| 531.85 | -0.14 | -0.14 |
| 507.87 | 0.62 | 0.62 |
| 507.87 | 0.36 | 0.36 |
| 493.84 | -0.03 | -0.03 |
| 569.96 | 0.41 | 0.41 |
| 599.00 | 0.26 | 0.26 |
| 589.87 | 1.56 | 1.56 |
| 488.83 | 0.50 | 0.50 |
| 568.33 | 0.91 | 0.91 |
| 537.89 | -0.02 | -0.02 |
| 507.82 | 0.06 | 0.06 |
| 534.94 | 0.93 | 0.93 |
| 536.33 | 2.23 | 2.23 |
| 590.85 | 0.95 | 0.95 |
| 583.35 | 0.42 | 0.42 |
| 507.87 | 0.36 | 0.36 |
| 612.30 | 3.01 | 3.01 |
| 598.27 | 2.36 | 2.36 |
| 520.27 | 1.52 | 1.52 |
| 523.87 | -0.67 | -0.67 |
| 537.96 | 1.73 | 1.73 |
| 537.89 | -0.02 | -0.02 |
| 541.91 | -0.02 | -0.02 |
| 534.29 | 1.91 | 1.91 |
| 598.27 | 2.36 | 2.36 |
| 521.90 | 0.75 | 0.75 |
| 507.87 | 0.36 | 0.36 |
| 548.28 | 1.09 | 1.09 |
| 585.23 | 1.10 | 1.10 |