Basic Information
ID: ALA4730280
Type: Binding
Description: Inhibition of recombinant Escherichia coli DNA gyrase AB expressed in Escherichia coli BL21 (DE3) using relaxed pJT519 DNA as substrate preincubated for 20 mins followed by 5'-BODIPY-TMR-TTCTTCTTCT addition and measured after 1 hr by fluorescence anisotropy
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4730280
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 487.44 | 1.20 | 1.20 |
| 455.41 | 0.44 | 0.44 |
| 469.43 | 0.75 | 0.75 |
| 480.42 | 0.31 | 0.31 |
| 455.41 | 0.44 | 0.44 |
| 455.41 | 0.44 | 0.44 |
| 454.42 | 1.04 | 1.04 |
| 498.48 | 0.87 | 0.87 |
| 624.63 | 0.01 | 0.01 |
| 480.42 | 0.31 | 0.31 |
| 485.43 | 0.45 | 0.45 |
| 624.63 | 0.01 | 0.01 |
| 455.41 | 0.44 | 0.44 |
| 583.58 | 0.18 | 0.18 |
| 541.54 | 0.41 | 0.41 |
| 470.42 | 0.02 | 0.02 |
| 528.50 | 0.50 | 0.50 |
| 471.86 | 0.95 | 0.95 |
| 528.50 | 0.23 | 0.23 |
| 512.50 | 0.50 | 0.50 |
| 514.47 | -0.16 | -0.16 |
| 485.43 | -0.07 | -0.07 |
| 529.49 | 0.46 | 0.46 |
| 499.46 | 0.58 | 0.58 |
| 454.42 | 1.04 | 1.04 |
| 498.48 | 0.50 | 0.50 |
| 547.53 | -0.05 | -0.05 |
| 479.43 | 0.91 | 0.91 |
| 528.50 | 0.23 | 0.23 |
| 469.43 | 0.75 | 0.75 |
| 484.45 | 0.48 | 0.48 |
| 499.46 | 0.49 | 0.49 |
| 540.51 | 0.27 | 0.27 |
| 499.46 | 0.49 | 0.49 |