Basic Information
ID: ALA4730447
Type: Binding
Description: Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated for 15 to 30 mins in presence of forskolin by fluorescent method relative to forskolin alone
Format: BAO_0000219
Organism: Homo sapiens
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4725414
Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated for 15 to 30 mins in presence of forskolin by fluorescent method relative to forskolin alone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4730447
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.33 | 3.12 | 3.12 |
| 380.35 | 3.94 | 3.94 |
| 348.33 | 3.42 | 3.42 |
| 358.45 | 3.91 | 3.91 |
| 380.35 | 3.94 | 3.94 |
| 412.39 | 2.51 | 2.51 |
| 380.35 | 4.12 | 4.12 |
| 364.33 | 3.12 | 3.12 |
| 310.36 | 2.41 | 2.41 |
| 352.29 | 3.25 | 3.25 |
| 366.32 | 3.56 | 3.56 |
| 378.35 | 3.13 | 3.13 |
| 366.32 | 3.56 | 3.56 |
| 392.36 | 4.26 | 4.26 |
| 370.28 | 3.39 | 3.39 |
| 382.32 | 3.26 | 3.26 |
| 338.41 | 3.22 | 3.22 |
| 380.35 | 4.12 | 4.12 |
| 370.28 | 3.39 | 3.39 |
| 394.37 | 4.33 | 4.33 |
| 334.30 | 3.11 | 3.11 |
| 348.33 | 3.42 | 3.42 |
| 380.35 | 3.60 | 3.60 |
| 348.33 | 3.42 | 3.42 |
| 342.40 | 3.55 | 3.55 |
| 348.33 | 3.42 | 3.42 |
| 380.35 | 4.12 | 4.12 |
| 366.32 | 3.56 | 3.56 |
| 359.31 | 2.98 | 2.98 |
| 352.29 | 3.25 | 3.25 |
| 376.38 | 4.23 | 4.23 |
| 296.33 | 2.10 | 2.10 |
| 380.35 | 3.94 | 3.94 |
| 375.22 | 3.73 | 3.73 |
| 378.35 | 3.13 | 3.13 |
| 392.36 | 4.26 | 4.26 |
| 402.30 | 4.13 | 4.13 |
| 418.30 | 4.01 | 4.01 |
| 372.43 | 3.77 | 3.77 |
| 420.29 | 4.27 | 4.27 |
| 392.36 | 4.26 | 4.26 |
| 388.47 | 3.92 | 3.92 |