Basic Information
ID: ALA4730523
Type: Binding
Description: Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescence based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epoxide hydratase(ALA2409)
Document: ALA4725418
Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4730523
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.37 | 2.99 | 2.99 |
| 469.43 | 4.64 | 4.64 |
| 504.70 | 5.35 | 5.35 |
| 450.41 | 5.25 | 5.25 |
| 437.50 | 3.45 | 3.45 |
| 426.42 | 2.91 | 2.91 |
| 424.43 | 2.65 | 2.65 |
| 408.43 | 2.77 | 2.77 |
| 409.40 | 4.30 | 4.30 |
| 447.47 | 3.40 | 3.40 |
| 424.47 | 5.27 | 5.27 |
| 421.38 | 3.03 | 3.03 |
| 405.38 | 3.15 | 3.15 |
| 369.40 | 2.31 | 2.31 |
| 520.61 | 2.80 | 2.80 |
| 391.35 | 2.76 | 2.76 |
| 510.42 | 5.46 | 5.46 |
| 423.37 | 3.28 | 3.28 |
| 447.46 | 4.17 | 4.17 |
| 527.52 | 5.31 | 5.31 |
| 442.52 | 3.76 | 3.76 |
| 419.40 | 3.45 | 3.45 |
| 527.52 | 5.31 | 5.31 |
| 433.43 | 3.78 | 3.78 |
| 405.38 | 3.15 | 3.15 |
| 543.52 | 5.19 | 5.19 |
| 525.53 | 5.05 | 5.05 |
| 475.98 | 4.80 | 4.80 |
| 534.64 | 3.52 | 3.52 |
| 395.34 | 2.74 | 2.74 |
| 405.38 | 3.15 | 3.15 |
| 441.53 | 4.15 | 4.15 |
| 509.53 | 5.17 | 5.17 |
| 419.40 | 3.54 | 3.54 |
| 406.27 | 3.43 | 3.43 |
| 390.44 | 2.65 | 2.65 |
| 435.40 | 3.15 | 3.15 |
| 406.36 | 2.54 | 2.54 |
| 405.38 | 3.15 | 3.15 |
| 527.52 | 5.31 | 5.31 |
| 459.52 | 4.29 | 4.29 |
| 433.43 | 3.93 | 3.93 |
| 355.37 | 2.27 | 2.27 |
| 477.51 | 4.43 | 4.43 |