Basic Information
ID: ALA4730723
Type: Binding
Description: Protac activity at CRBN/FAK in human PA1 cells assessed as induction of FAK degradation at 1 nM incubated for 8 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: PA-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4730723
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 950.92 | 2.43 | 2.43 |
| 964.94 | 2.10 | 2.10 |
| 906.86 | 2.41 | 2.41 |
| 977.98 | 3.76 | 3.76 |
| 949.93 | 3.03 | 3.03 |
| 919.90 | 2.69 | 2.69 |
| 993.98 | 3.05 | 3.05 |
| 1038.04 | ||
| 945.00 | 5.86 | 5.86 |
| 942.94 | 4.13 | 4.13 |
| 940.97 | 5.28 | 5.28 |
| 963.96 | 2.71 | 2.71 |
| 949.93 | 3.03 | 3.03 |
| 944.91 | 2.97 | 2.97 |
| 905.88 | 3.02 | 3.02 |
| 920.89 | 2.09 | 2.09 |
| 905.88 | 3.02 | 3.02 |
| 945.99 | 5.34 | 5.34 |
| 994.97 | 2.44 | 2.44 |
| 1009.00 | ||
| 993.98 | 3.05 | 3.05 |
| 1008.01 | ||
| 946.97 | 4.71 | 4.71 |
| 948.94 | 3.55 | 3.55 |