Basic Information
ID: ALA4730888
Type: Binding
Description: Inhibition of IKKalpha/IKKbeta in human HEK293T cells transfected with firefly luciferase gene assessed as inhibition of TNF-alpha-stimulated NF-kappaB signalling preincubated for 1 hr followed by TNF alpha stimulation measured after 3 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4730888
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.38 | 1.03 | 1.03 |
| 284.36 | 3.12 | 3.12 |
| 368.38 | 3.57 | 3.57 |
| 310.39 | 3.66 | 3.66 |
| 298.38 | 3.21 | 3.21 |
| 310.39 | 3.66 | 3.66 |
| 358.39 | 1.32 | 1.32 |
| 477.35 | 4.04 | 4.04 |
| 376.41 | 0.09 | 0.09 |
| 330.38 | 1.89 | 1.89 |
| 360.41 | 1.12 | 1.12 |
| 298.38 | 3.50 | 3.50 |
| 298.38 | 3.50 | 3.50 |
| 396.44 | 3.74 | 3.74 |
| 393.28 | 3.68 | 3.68 |
| 338.40 | 4.24 | 4.24 |
| 314.38 | 3.20 | 3.20 |
| 342.35 | 0.69 | 0.69 |
| 282.34 | 2.57 | 2.57 |
| 284.36 | 3.41 | 3.41 |
| 372.37 | 0.50 | 0.50 |
| 314.38 | 2.18 | 2.18 |
| 398.46 | 3.56 | 3.56 |
| 398.46 | 3.28 | 3.28 |
| 314.38 | 2.92 | 2.92 |